US Healthcare Professionals

The SENTINEL Cerebral Protection System (CPS)

Click here to view an overview of SENTINEL CPS

The SENTINEL Cerebral Protection System (CPS) was able to capture and remove embolic debris in 99% of TAVR patients, regardless of valve type and patient risk profile.1

In the SENTINEL US IDE, neurologist adjudicated peri-procedural (≤ 72 hours) stroke rate was reduced by 63% when SENTINEL CPS was used.1

SENTINEL CPS is the protection your patients need when they’re most vulnerable.
Consider Protected TAVR™ with SENTINEL CPS.

Protected TAVR patients had 63% fewer strokes, when compared to unprotected TAVR patients.1

The 63% peri-procedural (≤ 72 hours) stroke reduction1 was confirmed in an independent real-world academic study from Ulm Germany which demonstrated a compelling 70% reduction in neurologist adjudicated TAVR Stroke, and Stroke or Mortality in the first 7-days post TAVR.2

Click here to read a study in Journal of American College of Cardiology (JACC) that underscores how SENTINEL CPS reduced TAVR 7-Day All-Stroke and 7-Day All-Stroke or All-Cause Mortality by 70%.2

Click here to download a pdf of an overview of the SENTINEL CPS clinical program. Safety and Efficacy of Protected Cardiac Intervention: Clinical Evidence for SENTINEL Cerebral Embolic Protection, Ulrich Shäfer, Interventional Cardiology Review, Radcliffe Cardiology, Volume 12, Issue 2, Autumn 2017.

Click here to view the SENTINEL CPS large and growing compendium of Clinical Publications on Cerebral Embolic Protection.


  1. Kapadia et al. Cerebral Protection in Transcatheter Aortic Valve Replacement. J Am Coll Cardiol 2017;69:367–77
  2. Seeger J, et al. in press JACC 2017 SEPT

Expert Insights & Evidence

Article – Embolic Protection During Transcatheter Aortic Valve Replacement

Click here to read how Dr. Rinaldi’s thoughts on the importance of Cerebral Embolic Protection and his adoption of the SENTINEL Cerebral Protection System within his TAVR practice.

Video – View the Cerebral Embolic Protection Symposium at TVT 2018

Listen to expert insights on the evolution of Protected TAVR towards Standard of Care, a contemporary review of CEP evidence, TAVR stroke economics, perspectives on the future of Cerebral Protection and more!

Article – Reassurance to Both Physicians and Patients

Click here to read how Dr. Wöhrle explains how SENTINEL Cerebral Protection System provides reassurance to both physicians and patients.

Article – Which Patients Should Receive CEP

Click here to read Dr. Samir Kapadia’s perspectives that all patients should receive cerebral protection when undergoing TAVI procedures.

Caution: Federal (USA) law restricts this device to sale by or on the order of a physician. Click here for the Indication, Contraindications, Warnings, and Precautions.

Claret Medical is now a part of Boston Scientific.    SH-568319-AA