The Sentinel Cerebral Protection System (CPS)

Click here to view an overview of Sentinel CPS


The Sentinel Cerebral Protection System captures and removes embolic debris in 99%* of TAVI patients, regardless of valve type. In the SENTINEL pivotal US IDE, peri-procedural stroke rate was reduced by 63%* when Sentinel CPS was used.

Sentinel is the protection your patients need when they’re most vulnerable.
Consider Protected TAVI™ with Sentinel CPS.

Protected TAVI patients had 63% fewer strokes, when compared to unprotected TAVI patients.1

The 63% reduction was confirmed in an independent real-world academic study from Ulm Germany which demonstrated a compelling 70% reduction in neurologist adjudicated TAVI Stroke, and Stroke or Mortality in the first 7-days post TAVI.

Click here to read a study in Journal of American College of Cardiology (JACC) that underscores how Sentinel CPS reduces TAVI 7-Day All-Stroke and 7-Day All-Stroke or All-Cause Mortality by 70%.2

2. Seeger J, et al. in press JACC 2017 SEPT


Click here to download a pdf of an overview of the Sentinel CPS clinical program. Safety and Efficacy of Protected Cardiac Intervention: Clinical Evidence for Sentinel Cerebral Embolic Protection, Ulrich Shäfer, Interventional Cardiology Review, Radcliffe Cardiology, Volume 12, Issue 2, Autumn 2017.

Click here to view how Sentinel is driving the largest compendium of clinical publications on Cerebral Embolic Protection.

Expert Insights & Evidence

Video – View the Cerebral Embolic Protection Symposium at TVT 2018



Listen to expert insights on the evolution of Protected TAVR towards Standard of Care, a contemporary review of CEP evidence, TAVR stroke economics, perspectives on the future of Cerebral Protection and more!

Article – Reassurance to Both Physicians and Patients



Click here to read how Dr. Wöhrle explains how Sentinel Cerebral Protection System provides reassurance to both physicians and patients.

Article – Which Patients Should Receive CEP



Click here to read Dr. Samir Kapadia’s perspectives that all patients should receive cerebral protection when undergoing TAVI procedures.

Video – Claret Medical Scientific Symposium @ TCT 2017



Watch Claret Medical’s Scientific Symposium @ TCT 2017: Leadership in Protected TAVI with Sentinel as Standard of Care Chairs: Dr. Leon and Dr. Makkar. Faculty: Dr. Gada, Dr. Kapadia, Dr. Kodali, Dr. Messé, Dr. Siddiqui, Dr. Tchétché, Dr. Wöhrle

The Sentinel CPS has received the CE Mark and is commercially available in Europe.